Member Directory - TB Working Group

Chair: Susan Swindells

Objectives:

  • Guide product development and identify knowledge gaps requiring further research and resources for the prevention and treatment of tuberculosis (TB). Our goal is to identify the most promising drug candidates for development as long-acting/extended release (LA/ER) formulations.
  • Promote the development of LA/ER approaches for TB by building on previous modelling and preclinical work to evaluate novel long-acting formulations of TB drugs.
  • Develop additional applications to understand if in silico modelling can predict important drug-drug interactions involving LA/ER formulations, a particularly relevant issue for HIV and TB drugs where rifamycins are the source of many complex and significant interactions. Models will also be improved to provide dosing strategies for infants, children, adolescents, and pregnant women.

Interested in joining?
Please submit your request and your CV to Ana Cervantes. Acceptance requires a written nomination from a TB Working Group member and majority approval.

Susan Swindells is a Professor of Internal Medicine in the Section of Infectious Diseases at the University of Nebraska Medical Center, USA.

Conflict of Interest: Receives research grants to her institution from ViiV Healthcare.

Dr. Ammerman is a Researcher at Erasmus University Medical Center Rotterdam, Department of Medical Microbiology & Infectious Diseases; and an adjunct research associate at the Johns Hopkins Center for Tuberculosis Research. 

Conflict of Interest:  Receives research funding from Janssen Pharmaceutica.

Richard E. Chaisson, MD, is Professor of Medicine, Epidemiology, and International Health at Johns Hopkins University and Director of the Johns Hopkins Center for TB Research and the Center for AIDS Research.

Conflict of Interest: Receives consulting fees from Johnson & Johnson. Spouse has ownership interest in Merck.

Charles W. Flexner, MD, is the Principal Investigator of the Long Acting/Extended Release Antiretroviral Resource Program (LEAP).

Conflict of Interest: Receives consulting fees from Gilead Sciences, Merck, Janssen, ViiV Healthcare. Has an ownership interest in Navigen LLC, and receives grant funding from Gilead Sciences.

Hélène Hardy earned her Ph.D in clinical pharmacology from the University of Lille II, France. She has a Pharm.D from the University of Buffalo School of Pharmacy and an MPH from the University of Massachusetts.

Conflict of Interest: Has an ownership interest in Johnson & Johnson

Elisa H. Ignatius, MD, MSc is an Assistant Professor of Medicine in the Divisions of Infectious Diseases and Clinical Pharmacology at the Johns Hopkins University School of Medicine and Program Director for the Johns Hopkins Center for Nontuberculous Mycobacteria and Bronchiectasis.

Conflict of Interest: Has no real or apparent conflicts of interest to report.

Dr. Nuermberger is an Associate Professor of Medicine and International Health at Johns Hopkins University. His primary research interest is the experimental chemotherapy of TB.

Conflict of Interest:  Receives consulting fees from Janssen, Genentech and research funding from Janssen, TB Alliance.

David has >20 years of infectious disease drug discovery experience with a focus on HIV-1 and HCV.

Conflict of Interest: 

Andrew Owen is a Professor in the Department of Molecular and Clinical Pharmacology at the University of Liverpool. 

Conflict of Interest: Dr. Owen has reported having potential financial conflicts of interest within the past 12 months, or anticipated within the coming 12 months, with the following entities: Merck; GSK; Janssen; ViiV Healthcare

Dr. Chuck Peloquin received his BS in Pharmacy from the University of Connecticut and his Doctor of Pharmacy from the Philadelphia College of Pharmacy and Science.

Conflict of Interest: Has no real or apparent conflicts of interest to report.

Pharmaceutical Advocate to Médecins Sans Frontières on specific dossiers, such as access to Tuberculosis medicines.

Conflict of Interest: Has no real or apparent conflicts of interest to report.

Manuele Piccolis holds a PhD in Life Sciences from the University of Geneva and he has an extensive experience in metabolism.

Conflict of Interest: Spouse receives salary support from Lunaphore Tech.

Dr. Podany is currently an Assistant Professor in the department of pharmacy practice at the University of Nebraska Medical Center.

Conflict of Interest: Has no real or apparent conflicts of interest to report.

Dr. Rangaka is an Associate Professor within the Institute of Global Health, University College London (UCL), United Kingdom.

Conflict of Interest: Has no real or apparent conflicts of interest to report.

Bart Remmerie, Chem. Eng., graduated as a bio-engineer and as environmental engineer at Ghent University, Belgium. He started at Janssen (Bioanalysis) in 1994.

Conflict of Interest: As a Janssen employee I have a wage and shares from/in the company.

Kimberly Scarsi is an Associate Professor at the University of Nebraska Medical Center’s (UNMC) College of Pharmacy.

Conflict of Interest:Receives grant funding from Organon, LLC.